:root{--header-height:56px;--control-height:36px;--control-radius:10px;--primary-color:#2c3e50;--accent-color:#3498db;--border-color:#e0e0e0;--bg-header:#f8f9fa;--bg-panel:#fff;--shadow-soft:0 10px 24px #0000001f;--shadow-card:0 4px 12px #00000026}body,html{background-color:#fff;font-family:-apple-system,BlinkMacSystemFont,Segoe UI,Roboto,Helvetica,Arial,sans-serif;height:100%;margin:0;overflow:hidden}.app-container{display:flex;flex-direction:column;height:100vh;width:100vw}.app-header{background-color:#f8f9fa;background-color:var(--bg-header);border-bottom:1px solid #e0e0e0;border-bottom:1px solid var(--border-color);box-sizing:border-box;flex-wrap:wrap;gap:12px;height:auto;justify-content:space-between;min-height:56px;min-height:var(--header-height);padding:8px 16px;z-index:20}.app-header,.app-title{align-items:center;display:flex}.app-title{color:#2c3e50;color:var(--primary-color);flex:1 1;font-size:18px;font-weight:600;gap:14px;min-width:0}.app-title .brand{font-weight:700;white-space:nowrap}.header-search{flex:1 1;max-width:520px;min-width:180px}.header-controls{align-items:center;display:flex;gap:10px}.toolbar-group{align-items:center;display:flex;gap:8px}.status-pill{align-items:center;background:#fff;border:1px solid #e0e0e0;border:1px solid var(--border-color);border-radius:999px;color:#555;display:inline-flex;font-size:12px;height:36px;height:var(--control-height);padding:0 10px;white-space:nowrap}.status-pill.ready{background:#f2fbf5;border-color:#bfe6cd;color:#1b7f3a}.status-pill.loading{background:#fff8e5;border-color:#ffe6ad;color:#7a5a00}.action-btn{align-items:center;border:1px solid #0000;border-radius:10px;border-radius:var(--control-radius);cursor:pointer;display:inline-flex;font-size:13px;font-weight:600;gap:6px;height:36px;height:var(--control-height);justify-content:center;line-height:1;padding:0 14px;transition:background-color .15s,border-color .15s,opacity .15s;-webkit-user-select:none;user-select:none}.action-btn:disabled{cursor:not-allowed;opacity:.55}.action-btn.primary{background-color:#3498db;background-color:var(--accent-color);color:#fff}.action-btn.primary:hover:not(:disabled){background-color:#2980b9}.action-btn.secondary{background:#fff;border-color:#e0e0e0;border-color:var(--border-color);color:#2c3e50;color:var(--primary-color)}.action-btn.secondary:hover:not(:disabled){background:#f8f9fa}.action-btn.icon{font-size:16px;padding:0;width:36px;width:var(--control-height)}.action-btn.danger{background:#fff5f5;border-color:#ffd1d1}.action-btn.secondary.active-tool{background-color:#3498db;background-color:var(--accent-color);border-color:#3498db;border-color:var(--accent-color);color:#fff}.workspace{display:flex;flex:1 1;min-height:0;width:100%}.editor-panel{background:#fff;background:var(--bg-panel);border-right:1px solid #e0e0e0;border-right:1px solid var(--border-color);flex:1 1;min-width:0;position:relative}.editor-panel .Ketcher-root{border:none!important;height:100%!important;width:100%!important}.viewer-panel{background-color:#fff;background-color:var(--bg-panel);flex:1 1;position:relative}.viewer-panel canvas{height:100%!important;outline:none;width:100%!important}.status-indicator{background:#ffffffd9;border-radius:8px;bottom:10px;color:#bdc3c7;font-size:12px;padding:4px 8px;pointer-events:none;position:absolute;right:10px}.cluster-menu{border-radius:12px;left:16px;top:16px;width:180px}.cluster-menu,.properties-card{backdrop-filter:blur(6px);-webkit-backdrop-filter:blur(6px);background:#ffffffd9;border:1px solid #00000014;box-shadow:0 4px 12px #00000026;box-shadow:var(--shadow-card);display:flex;flex-direction:column;overflow:hidden;position:absolute;z-index:10}.properties-card{border-radius:12px;bottom:16px;max-width:calc(100% - 32px);right:16px;width:320px}.cluster-header,.properties-header{background:#f8f9fa;border-bottom:1px solid #eee;color:#555;font-size:12px;font-weight:700;letter-spacing:.5px;padding:10px 12px;text-transform:uppercase}.clickable-header{align-items:center;cursor:pointer;display:flex;justify-content:space-between;transition:background-color .15s ease;user-select:none;-webkit-user-select:none}.clickable-header>span{cursor:pointer}.toggle-icon{align-items:center;background:#0000;border-radius:4px;color:#888;display:flex;font-size:14px;font-weight:700;height:22px;justify-content:center;margin-left:16px;transition:background-color .2s,color .2s;width:22px}.clickable-header:hover .toggle-icon{background:#00000014;color:#333}.panel-collapse{display:grid;grid-template-rows:0fr;transition:grid-template-rows .3s cubic-bezier(.4,0,.2,1)}.panel-collapse.open{grid-template-rows:1fr}.panel-inner{min-height:0;overflow:hidden}.cluster-list{max-height:45vh;overflow-y:auto}.properties-table{grid-gap:6px;display:grid;font-size:13px;gap:6px;max-height:55vh;overflow-y:auto;padding:8px 12px}.cluster-item{border-bottom:1px solid #f5f5f5;cursor:pointer;padding:10px 12px;transition:background .15s}.cluster-item:hover{background:#f0f7ff}.cluster-item.active{background:#e1effe;border-left:3px solid #3498db;border-left:3px solid var(--accent-color)}.cluster-name{color:#333;display:block;font-size:14px;font-weight:600}.cluster-meta{color:#888;display:block;font-size:11px;margin-top:4px}.properties-table>div{grid-gap:8px;align-items:start;border-bottom:1px solid #f7f7f7;display:grid;gap:8px;grid-template-columns:110px 1fr;padding:3px 0}.properties-table>div:last-child{border-bottom:none}.properties-table span:first-child{color:#666;font-weight:600}.properties-table span:last-child{color:#222;word-break:break-word}.pubchem-search{max-width:none;position:relative;width:100%}.pubchem-inputWrap{align-items:center;background:#fff;border:1px solid #e0e0e0;border:1px solid var(--border-color);border-radius:10px;border-radius:var(--control-radius);box-sizing:border-box;display:flex;gap:8px;height:36px;height:var(--control-height);padding:0 8px}.pubchem-inputWrap.disabled{opacity:.6}.pubchem-icon{font-size:14px;opacity:.7}.pubchem-input{background:#0000;border:none;font-size:14px;height:100%;outline:none;width:100%}.pubchem-go{background:#eef5ff;border:none;border-radius:8px;border-radius:calc(var(--control-radius) - 2px);color:#1f5ea8;cursor:pointer;font-weight:700;height:28px;height:calc(var(--control-height) - 8px);padding:0 10px}.pubchem-go:disabled{cursor:not-allowed;opacity:.5}.pubchem-dropdown{background:#fff;border:1px solid #e0e0e0;border:1px solid var(--border-color);border-radius:12px;box-shadow:0 10px 24px #0000001f;box-shadow:var(--shadow-soft);left:0;overflow:hidden;position:absolute;right:0;top:calc(100% + 6px);z-index:50}.pubchem-list{list-style:none;margin:0;max-height:280px;overflow:auto;padding:6px 0}.pubchem-item{cursor:pointer;font-size:14px;padding:10px 12px}.pubchem-item.active,.pubchem-item:hover{background:#f0f7ff}.pubchem-hint{color:#666}.pubchem-error,.pubchem-hint{font-size:12px;padding:10px 12px}.pubchem-error{background:#fff2f4;border-bottom:1px solid #ffd6dc;color:#b00020}@media (max-width:900px){.header-search{max-width:360px}.cluster-menu{width:170px}}@media (max-width:768px){.app-header{align-items:flex-start;flex-direction:column;gap:12px;height:auto;padding:12px 16px}.app-title{flex-wrap:wrap;width:100%}.header-search{margin-top:4px;max-width:100%;min-width:100%}.header-controls{-webkit-overflow-scrolling:touch;gap:12px;overflow-x:auto;padding-bottom:6px;width:100%}.toolbar-group{flex-shrink:0}.action-btn.primary,.action-btn.secondary{white-space:nowrap}.workspace{flex:1 1;flex-direction:column;height:0}.editor-panel,.viewer-panel{border-right:none;flex:1 1;min-height:0;width:100%}.editor-panel{border-bottom:2px solid #e0e0e0;border-bottom:2px solid var(--border-color)}.cluster-menu{left:8px;top:8px;width:160px}.properties-card{bottom:8px;max-width:300px;right:8px;width:calc(100% - 16px)}.cluster-header,.properties-header{font-size:11px;padding:8px 10px}}@media (max-width:1100px) and (min-width:769px){.header-search{max-width:300px}.app-title{flex:1 1 100%;margin-bottom:4px}.header-controls{justify-content:space-between;width:100%}}